Why Continuous Oral Delivery?
Sustained delivery has the potential to enhance many oral therapies. Continuous Oral Delivery provides controlled delivery over several hours for therapies that benefit from prolonged oral exposure or gradual swallowing.
Sustained Delivery
Provides a predetermined quantity of formulation over a controlled period of time
Local or Systemic Therapy
Supports therapies intended for local action within the oral cavity or systemic delivery via the gastrointestinal tract.
Formulation Flexible
Compatible with a broad range of fluid formulations such as oils, gel and paste formulation. Â
The Contoral Platform
The Contoral platform combines a reusable oral appliance with disposable pre-filled capsules to enable comfortable, sustained administration of compatible fluid formulations within the oral cavity.
Appliance Integration
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Our proprietary connector securely attaches the delivery capsule to a wide range of custom oral appliances, including night guards, sleep appliances, retainers, dentures, and other dental devices.
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Delivery Capsule
Disposable, pre-filled capsules are compatible with a broad range of fluid formulations and are easily replaced as therapy continues.
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Engineered Delivery
Pressurized capsule designs administer formulations at the intended delivery profile. Capsule geometry, pressurization technology, and positioning within the oral cavity can be tailored for different therapeutic applications.
Clinical Integration
Designed to fit naturally into existing dental workflows using digital scanning, custom appliance fabrication, and routine follow-up care.
Capsule Engineering
Delivering a formulation continuously over several hours requires more than a container. Every part of the capsule is engineered to achieve the right balance of delivery performance, patient comfort, and manufacturability.
Pressure
The capsule creates a steady driving force to deliver the formulation. Depending on the application, this pressure can be generated using spring-based or chemical technologies.
Delivery Control
The capsule is engineered to release the formulation at a controlled rate. Flow-control features, including outlet geometry and filters, regulate how the formulation is delivered.
Capsule Design
The capsule's size and shape affect both how the formulation is delivered and how comfortable it is to wear. Each design is optimized for the intended therapy.
Clinical Workflow
A seamless integration into professional dental practice, from the initial consultation to nightly therapeutic relief.
Visit Dentist
Oral
Scan
Appliance Manufact-uring
Appliance Fitting
Capsule Purchase
Deliver all night
Wake up refreshed
One Platform. Multiple Applications.
Continuous Oral Delivery is a versatile therapeutic platform, engineered for a range of clinical applications from oral health to systemic medicine.
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Parkinson's Disease
Pharmaceutical Foundation
Commercialising Today
Advancing Future Therapies
Sustained hydration and lubrication for long-term xerostomia relief.
Chronic Dry Mouth
Dentist-led Oral Therapies
Available for future development with an appropriate pharmaceutical partner
Targeted treatment for periodontal disease and oral health optimization.
Dental-Medical Integration
Bridging the gap between oral health and systemic pharmaceutical delivery.
Protected Innovation
Continuous Oral Delivery is built on an established international patent foundation and a growing portfolio of next-generation innovation.
Established IP Foundation
9 Patents Licensed
An international portfolio of issued patents protects the foundational Continuous Oral Delivery technology licensed by Contoral.
Contoral-developed Innovation
Contoral is building on this foundation with new patent filings covering advances in fluid delivery, connector technology and integration with oral appliances.
Patent pending
Built for Collaboration
Formulation Partners
Pharmaceutical • Oral Care • Consumer Health
Integrate existing or new formulations into the Contoralâ„¢ platform to create differentiated therapeutic products.
Pharmaceuticals · Oral moisturizers · Preventive therapies
Dental Ecosystem
Oral Appliance Companies • Dental Laboratories • Dentists
Bring Continuous Oral Delivery to patients by integrating our capsule with custom oral appliances and digital dental workflows.
Sleep appliances · Night guards · Retainers · Dentures
Clinical Innovation
Academic Centres • Researchers • Clinical Partners
Generate clinical evidence, explore new therapeutic applications and establish Continuous Oral Delivery as a new treatment modality.
Clinical research · Bioavailability studies · New therapeutic indications